Cardioprotective Effects and Mechanisms of Saponins on Cardiovascular Disease

Cardiovascular disease (CVD), a leading cause of morbidity and mortality, is among the most prevalent health problems worldwide effective strategies for its prevention treatment are urgently required. In this regard, increasing research has demonstrated that natural drugs offer antihypertensive, antiatherosclerotic, cardioprotective activities, many applied widely CVD manifestations such as myocardial infarction, peripheral vascular diseases, coronary heart disease. Natural have significant advantages in due to their efficacy safety profiles. Saponins an important class active components plant products play role CVD. This review covers up-to-date information on saponins concerning effects mechanisms action.